The 2025–26 respiratory virus season, which spans November through April, is around the corner. Between September and October, we encourage community members to prepare by getting vaccinated. The Champaign-Urbana Public Health District provides weekly reports on the “big three” respiratory illnesses—COVID-19, influenza, and Respiratory Syncytial Virus (RSV). These reports draw on both laboratory data and emergency department visits, offering valuable context for respiratory virus surveillance, particularly when COVID-19, seasonal influenza, and RSV are circulating at the same time. Please note that all data are preliminary and may change as additional information becomes available.